Our bodies develop form embryonic stem cells (ESCs). When we are young, stem cells are rich in our body which means we can grow quickly and have very soft and regenerative skin.
However, as we get older and are thus exposed to many kinds of stress factors, the stem cells rapidly lose vitality and become extinct, which results in losing our physical activity and showing the rough wrinkled skin due to limited supply of new epithelial cells.
Thus, to help with health maintenance and to overcome incurable diseases, it is possible to restore injured cells and tissues by transplanting stem cells extracted from adipose tissue, umbilical cord, amniotic membrane or other tissues in which lots of stem cells remain.
“It is possible to restore injured cells and tissues by transplanting stem cells”
Prevention of cell deathPrevents cell death and tissue damage via signal transduction and anti-oxidative functions by secreting growth factors (GFs) and neurotrophic factors (NFs).
Immunoregulation & anti-inflammationImmunoregulatory activity strengthens the normal immune function, relieves any allergic reaction, and inhibits inflammation.
Tissue regeneration & wound healingStem cells migrate to the injured body regions and replace the deleted cells and tissues. They also regenerate the damaged cells and tissues by supplying GFs and NFs.
Blood flow improvementHelp with the tissue regeneration by improving blood flow through stimulation of hematopoiesis and participation in angiogenesis.
Trans-differentiationDifferentiate into nerve cells, cartilage cells, vascular cells, and other functional cells that are specifically required for tissue regeneration and functional recovery.
NetworkingInvolved in the nervous system and endocrine system to participate in the neural transmission and hormonal regulation.
Designed Cells’ stem cells for the treatment of central nervous system (CNS) diseases are induced neural stem cells (iNSCs) obtained through ethical procedures (IRB). The cells are from safe autologous adipose-derived stem cells (ADSCs) or tissue-compatible amniotic membrane stem cells (AMSCs), and especially provide excellent therapeutic efficacies by expressing target-specific functional genes (Core-technology 1).
Another our advanced technology is to obtain high-concentrations (50~100 folds) of stem cell exosomes from the functional gene-encoding stem cells (Core-technology 2).
| Item | USBSCs / BMSCs / ADSCs | INSC encoding functional genes* | Stem cell exosomes (contents: 50-100 folds)* | Stem cell exosomes (contents: 50-100 folds)* |
|---|---|---|---|---|
| Tumor formation | None | None | None | None |
| Effectiveness (CNS diseases) | Limited | Best (whole cycle of disease) | Excellent (early-middle terms of disease) | Excellent (early-middle terms of disease) |
| Brain penetration | Sufficient (ICV) / Limited (IV) | Sufficient (ICV) / Limited (IV) | Sufficient (IV/nasal) | Sufficient (IV/nasal) |
| Compatibility & survival | Ordinary | Excellent | Excellent (neuroregeneration) | Excellent (neuroregeneration) |
| Adverse effects | Excellent (autologous) / Ordinary (allogeneic) | Excellent (autologous) | Best | Best |
| Collecting times | Repeated | Repeated | Once (immortalized) | Once (immortalized) |